11 COMMON REASONS FOR FATIGUE

A HOLISTIC AND SCIENTIFIC PERSPECTIVE

Fatigue is more than just a feeling of tiredness; it is a sign of imbalance in both the body and mind. Across ancient traditions like Ayurveda and Traditional Chinese Medicine (TCM), as well as modern scientific research, the causes of fatigue are deeply interconnected and stem from lifestyle, diet, toxins and environmental factors.

1. Poor Sleep Quality & Circadian Rhythm Disruptions

One of the most common reasons for fatigue is poor sleep quality and disruptions in the body’s natural circadian rhythm. In Ayurveda, sleep (Nidra) is considered one of the three pillars of health, and an imbalance in Vata and Pitta doshas can lead to restlessness, insomnia, and mental exhaustion. TCM views sleep as essential for replenishing Kidney Qi and Liver Blood, both of which are crucial for sustained energy. Neuroscience emphasizes that morning sunlight exposure is key to regulating the body’s internal clock, while artificial blue light at night suppresses melatonin, leading to poor sleep and increased daytime fatigue.

2. Nutrient Deficiencies (Iron, B12, Magnesium, etc.)

Another major factor is nutrient deficiencies, particularly iron, B12, and magnesium. In Ayurveda and TCM, low energy is often linked to blood deficiency, which can be replenished through iron-rich foods like leafy greens, dates, and bone broth. Scientific studies confirm that iron and B12 are essential for oxygen transport in the body, and magnesium plays a crucial role in cellular energy production. Without these nutrients, symptoms like fatigue, brain fog, and weakness become common.

3. Chronic Stress & Cortisol Dysregulation

Chronic stress is a widespread cause of fatigue, depleting both the nervous system and hormonal balance. Ayurveda attributes this to excess Vata, the wind energy, which creates an overactive mind and nervous system burnout. In TCM, chronic stress is linked to the depletion of Kidney Jing, the life essence that governs energy and vitality. Modern science supports this, showing that prolonged stress keeps cortisol levels elevated, leading to disrupted sleep, metabolic slowdown, and persistent exhaustion.

4. Sedentary Lifestyle & Lack of Movement

A sedentary lifestyle can also contribute to fatigue. In Ayurveda and TCM, stagnation of Qi or Prana results in sluggishness, emphasizing the importance of daily movement practices like yoga or Tai Chi. Scientifically, regular exercise has been proven to enhance mitochondrial function, improve circulation, and boost dopamine levels, all of which contribute to sustained energy and motivation and will power.

5. Dehydration & Poor Diet Choices

Dehydration and poor diet choices play a critical role in energy depletion. Ayurveda highlights the importance of keeping Agni (digestive fire) strong through warm water and easily digestible foods. Modern science confirms that even mild dehydration can cause significant drops in energy, cognitive function, and overall well-being. Processed foods, excessive sugar, and caffeine crashes also contribute to energy imbalances.

6. Gut Microbiome Imbalances

Another hidden cause of fatigue lies in gut health. Ayurveda links poor gut health to weakened Ojas (vitality essence), leading to a lack of sustained energy. TCM also considers the gut as the center of Qi production. Scientific studies reveal that an imbalanced gut microbiome disrupts neurotransmitter production, leading to low serotonin and dopamine levels, which can trigger both mental and physical exhaustion.

7. Hormonal Imbalances (Thyroid, Adrenals, etc.)

Fatigue can also result from hormonal imbalances such as hypothyroidism or adrenal dysfunction. Ayurveda and TCM view these issues as deficiencies in Kidney Qi and Ojas, which regulate metabolism and energy levels. Modern medicine explains that an underactive thyroid (low T3/T4 hormones) slows down metabolism, while adrenal fatigue disrupts cortisol and energy production.

8. Emotional Burnout & Mental Overload

Emotional exhaustion is another key contributor to fatigue. Ayurveda considers excess Rajas (hyperactivity in the mind) as a major cause of mental burnout. Meditation, breathwork, and herbal adaptogens like Ashwagandha and Brahmi help restore balance. From a neuroscientific perspective, prolonged mental fatigue reduces dopamine and motivation, making even small tasks feel overwhelming.

9. Environmental Toxins & Heavy Metal Exposure

The accumulation of toxins in the body can lead to sluggishness and chronic fatigue. Ayurveda describes these as Ama (toxins), which block the natural flow of Prana. TCM similarly believes that toxins disrupt Qi circulation. Modern research confirms that exposure to heavy metals like lead and mercury interferes with mitochondrial function, leading to low energy and brain fog.

10. Undiagnosed Medical Conditions (e.g., Sleep Apnea)

Sometimes, fatigue is a symptom of an underlying medical condition. Ayurveda and TCM believe that blocked Qi and poor Prana circulation due to chronic illness can drain energy. From a medical standpoint, conditions like sleep apnea reduce oxygen intake, leading to frequent nighttime awakenings and daytime exhaustion.

11. Fatigue through Corona, Paost-Vac & Long Covid

One of the most common complaints post-COVID or post-vaccine is chronic fatigue syndrome (CFS)-like symptoms, which can persist for months. Ayurveda and TCM view post-viral fatigue as a depletion of Ojas and Qi, requiring deep nourishment and rest. In modern medicine, Long COVID is linked to immune system dysregulation, mitochondrial damage, and lingering inflammation. Supporting mitochondrial health with CoQ10, NAD+, and anti-inflammatory foods can aid recovery. Herbs like Ashwagandha, Astragalus, and medicinal mushrooms (Reishi, Cordyceps) help strengthen immunity and energy levels.

SUMMARY

Fatigue is not just about getting more rest—it requires a holistic approach that aligns with natural rhythms, proper nutrition, stress management, movement, and detoxification. By integrating ancient wisdom with modern science, we can restore balance and vitality. Stay tuned for deeper insights into each of these causes in the upcoming series!